Dr Eugene Fine is clinical professor in the Department of Radiology (Nuclear Medicine) at Albert Einstein College of Medicine and Downstate Medical Cente. He and his colleagues are studying effects of ketogenic diets on aggressive cancers. They have published a pilot study (10 patients) of a ketogenic diet in cancers. The extent of ketosis correlated with stable disease or partial remission. They are also studying mechanisms by which ketone bodies inhibit cancer cell growth and energy metabolism. Finally, they are preparing to combine ketogenic diets with drug therapies, testing first in animals. THey hypothesize, ultimately, that improved efficacy due to the ketogenic diet will reduce toxic drug doses, improving both outcomes and quality of life.