By Marika Sboros

It was once revered as “the world’s most prestigious scientific organisation” devoted to independent, evidence-based medicine. Today, the Cochrane Collaboration is in “moral crisis”, say insiders. They are predicting the beginning of the organisation’s end.

Critics say that the Collaboration has “lost its way”. It has grown too close to the drug industry and too far from delivering “trusted evidence”.

That follows the expulsion of one of its most high-profile members, Dr Peter C Gøtzsche at its annual board meeting in Edinburgh, Scotland recently.

The Board has accused Gøtzsche of bringing the organisation into disrepute. That followed Gøtzsche’s harsh criticism of a Cochrane review of the evidence for the human papillomavirus (HPV) vaccine. He and his team called it “incomplete and biased”.

Gøtzsche is unrepentant and says that the Cochrane has “a moral governance crisis”. Four more board members have resigned in protest at Gøtzsche’s shock sacking.